1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. cis-11,14-Eicosadienoic acid methyl ester

cis-11,14-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5’-monophosphate dehydrogenase (Ki=3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki=3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance.3 Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.

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cis-11,14-Eicosadienoic acid methyl ester Chemical Structure

cis-11,14-Eicosadienoic acid methyl ester Chemical Structure

CAS No. : 61012-46-2

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Description

cis-11,14-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5’-monophosphate dehydrogenase (Ki=3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki=3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance.3 Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.

Molecular Weight

322.53

Formula

C21H38O2

CAS No.
SMILES

CCCCC/C=C\C/C=C\CCCCCCCCCC(OC)=O

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cis-11,14-Eicosadienoic acid methyl ester Related Classifications

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cis-11,14-Eicosadienoic acid methyl ester
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HY-141635
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