2. Peptides
  3. Peptide and Derivatives
  4. Peptide Epitopes
  5. CLIP (86-100)

CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site.

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CLIP (86-100) Chemical Structure

CLIP (86-100) Chemical Structure

CAS No. : 648881-58-7

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Based on 1 publication(s) in Google Scholar

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CLIP (86-100) Related Antibodies

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Description

CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site[1].

Molecular Weight

1674.10

Formula

C72H128N20O19S3
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Pro-Val-Ser-Lys-Met-Arg-Met-Ala-Thr-Pro-Leu-Leu-Met-Gln-Ala
Sequence Shortening

PVSKMRMATPLLMQA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (59.73 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5973 mL 2.9867 mL 5.9734 mL
5 mM 0.1195 mL 0.5973 mL 1.1947 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.5973 mL 2.9867 mL 5.9734 mL 14.9334 mL
5 mM 0.1195 mL 0.5973 mL 1.1947 mL 2.9867 mL
10 mM 0.0597 mL 0.2987 mL 0.5973 mL 1.4933 mL
15 mM 0.0398 mL 0.1991 mL 0.3982 mL 0.9956 mL
20 mM 0.0299 mL 0.1493 mL 0.2987 mL 0.7467 mL
25 mM 0.0239 mL 0.1195 mL 0.2389 mL 0.5973 mL
30 mM 0.0199 mL 0.0996 mL 0.1991 mL 0.4978 mL
40 mM 0.0149 mL 0.0747 mL 0.1493 mL 0.3733 mL
50 mM 0.0119 mL 0.0597 mL 0.1195 mL 0.2987 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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CLIP (86-100) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CLIP (86-100)648881-58-7OthersinvariantchainproteasesfragmentsimmunemarkerInhibitorinhibitorinhibit

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