2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Copper tripeptide

Copper tripeptide  (Synonyms: GHK-Cu)

Cat. No.: HY-P0063 Purity: 99.52%
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Copper tripeptide (GHK-Cu) is a tripeptide. During wound healing, copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Copper tripeptide Chemical Structure

Copper tripeptide Chemical Structure

CAS No. : 89030-95-5

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100 mg USD 55 In-stock
250 mg USD 90 In-stock
500 mg USD 130 In-stock
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Based on 1 publication(s) in Google Scholar

Copper tripeptide Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Copper tripeptide

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Copper tripeptide (GHK-Cu) is a tripeptide. During wound healing, copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration[1].

In Vitro

Copper tripeptide (1 nM; 0-96 hours) affects irradiated fibroblasts such that their population-doubling times approximated that of controls[1].
? Copper tripeptide (1 nM; 0-120 hours) significantly produces more basic fibroblast growth factors than normal controls at a 24-hour interval of irradiated fibroblasts[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Copper tripeptide Related Antibodies
Molecular Weight

401.91

Formula

C14H22CuN6O4
CAS No.
Appearance

Solid

Color

Light blue to blue

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (124.41 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4881 mL 12.4406 mL 24.8812 mL
5 mM 0.4976 mL 2.4881 mL 4.9762 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.4881 mL 12.4406 mL 24.8812 mL 62.2030 mL
5 mM 0.4976 mL 2.4881 mL 4.9762 mL 12.4406 mL
10 mM 0.2488 mL 1.2441 mL 2.4881 mL 6.2203 mL
15 mM 0.1659 mL 0.8294 mL 1.6587 mL 4.1469 mL
20 mM 0.1244 mL 0.6220 mL 1.2441 mL 3.1101 mL
25 mM 0.0995 mL 0.4976 mL 0.9952 mL 2.4881 mL
30 mM 0.0829 mL 0.4147 mL 0.8294 mL 2.0734 mL
40 mM 0.0622 mL 0.3110 mL 0.6220 mL 1.5551 mL
50 mM 0.0498 mL 0.2488 mL 0.4976 mL 1.2441 mL
60 mM 0.0415 mL 0.2073 mL 0.4147 mL 1.0367 mL
80 mM 0.0311 mL 0.1555 mL 0.3110 mL 0.7775 mL
100 mM 0.0249 mL 0.1244 mL 0.2488 mL 0.6220 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Copper tripeptide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Copper tripeptide89030-95-5GHK-CuEndogenous Metabolitehuman plasmasalivaurineinflammatoryfibroblastchemoattractantendothelialcollagenelastinproteoglycanand glycosaminoglycanInhibitorinhibitorinhibit

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