Cristacarpin (Synonyms: Erythrabyssin I; Erythrabissin I)

Cat. No.: HY-N3642: FAQs
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Cristacarpin can be extracted from the stem bark of Erythrina suberosa, promotes endoplasmic reticulum (ER) stress, leading to sublethal reactive oxygen species (ROS) production and ultimately cell death through senescence.

For research use only. We do not sell to patients.

Cristacarpin Chemical Structure

CAS No. : 74515-47-2

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Description

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	IC₅₀	3.36 μM Compound: 8	Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28189086]

Molecular Weight

354.40

Formula

C₂₁H₂₂O₅

CAS No.

74515-47-2

SMILES

O[C@]12[C@](OC3=C(C/C=C(C)\C)C(OC)=CC=C32)([H])C4=CC=C(O)C=C4OC1

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Chakraborty S, et al. Cristacarpin promotes ER stress-mediated ROS generation leading to premature senescence by activation of p21(waf-1). Age (Dordr). 2016 Jun;38(3):62. [Content Brief]

Cristacarpin Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cristacarpin74515-47-2Erythrabyssin I Erythrabissin IOthersCell Senescence AcceleratorInhibitorinhibitorinhibit

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