2. Cell Cycle/DNA Damage
  3. LIM Kinase (LIMK)
  4. CRT 0105446

CRT 0105446 (compound 22d) is a LIMK1 inhibitor, with an IC50 of 8 nM.

For research use only. We do not sell to patients.

CRT 0105446 Chemical Structure

CRT 0105446 Chemical Structure

CAS No. : 1661846-05-4

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CRT 0105446 Related Antibodies

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Description

CRT 0105446 (compound 22d) is a LIMK1 inhibitor, with an IC50 of 8 nM[1].

In Vitro

CRT 0105446 (compound 22d) inhibits the invasion of the cells through matrigel at a concentration of 3 µM, whilst not significantly affecting cell viability even at the higher compound concentration of 10 µM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CRT 0105446 Related Antibodies
Molecular Weight

421.44

Formula

C20H18F3N3O2S
CAS No.
SMILES

CC(C(NC1=NC=C(S1)C2=C(C=NC=C2)C3=CC=C(C=C3C(F)(F)F)OC)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CRT 0105446 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CRT 01054461661846-05-4CRT0105446CRT-0105446LIM Kinase (LIMK)LIMKsLIMK1anti-invasivecancerRho GTPasesInhibitorinhibitorinhibit

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