2. Anti-infection
  3. Bacterial
  4. Cyclic L27-11

Cyclic L27-11 is a cyclic peptide-like antibiotic with strong antibacterial activity against specific bacteria such as Pseudomonas sp. Cyclic L27-11 shows nanomolar antibacterial activity against Pseudomonas sp., especially Pseudomonas aeruginosa. Cyclic L27-11 interferes with the function of bacterial outer membrane protein LptD, preventing the normal transport of lipopolysaccharide (LPS), leading to the accumulation of membrane-like substances in bacterial cells, which in turn affects the survival of bacteria. Cyclic L27-11 can be used in the development of antibacterial agents.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Cyclic L27-11 Chemical Structure

Cyclic L27-11 Chemical Structure

CAS No. : 1221423-80-8

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Cyclic L27-11 Related Antibodies

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Description

Cyclic L27-11 is a cyclic peptide-like antibiotic with strong antibacterial activity against specific bacteria such as Pseudomonas sp. Cyclic L27-11 shows nanomolar antibacterial activity against Pseudomonas sp., especially Pseudomonas aeruginosa. Cyclic L27-11 interferes with the function of bacterial outer membrane protein LptD, preventing the normal transport of lipopolysaccharide (LPS), leading to the accumulation of membrane-like substances in bacterial cells, which in turn affects the survival of bacteria. Cyclic L27-11 can be used in the development of antibacterial agents[1].

Molecular Weight

1805.22

Formula

C87H141N27O15
CAS No.
Sequence

cyclo(Thr-Trp-Leu-Lys-Lys-Arg-Arg-Trp-Lys-Lys-Ala-Lys-{d-Pro}-Pro)
Sequence Shortening

cyclo(TWLKKRRWKKAK-{d-Pro}-P)
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cyclic L27-11 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclic L27-111221423-80-8BacterialCyclic peptideantibacterial activityouter membrane proteinsLPSPseudomonas sp.Inhibitorinhibitorinhibit

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