2. Neuronal Signaling
  3. Tau Protein Amyloid-β
  4. D-688

D-688 is an inhibitor of Tau and Aβ. D-688 can reverse Aβ1–42-induced toxicity in SH-SH5Y cells and has significant neuroprotective properties. D-688 can improve the survival rate of Drosophila melanogaster expressing the human tau protein isoform (2N4R).

For research use only. We do not sell to patients.

D-688 Chemical Structure

D-688 Chemical Structure

CAS No. : 2276762-07-1

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D-688 Related Antibodies

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Description

D-688 is an inhibitor of Tau and Aβ. D-688 can reverse Aβ1–42-induced toxicity in SH-SH5Y cells and has significant neuroprotective properties. D-688 can improve the survival rate of Drosophila melanogaster expressing the human tau protein isoform (2N4R)[1].

Molecular Weight

421.51

Formula

C25H28FN3O2
CAS No.
SMILES

OC1=CC=C(C=C1O)C2=CC=C(C=C2)N3CCN(CC3)CCNCC4=CC=C(C=C4)F
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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D-688 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-6882276762-07-1D688D 688Tau ProteinAmyloid-ββ-amyloid peptideAβAbetaAlzheimer’s DiseaseNeurofibrillary TanglesAmyloid Precursor ProteinPolyphenolDrosophila FlyTransmission Electron MicroscopyInhibitorinhibitorinhibit

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HY-169197
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