2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. Decylubiquinone

Decylubiquinone is an analog of ubiquinone (coenzyme Q10). Decylubiquinone blocks reactive oxygen species (ROS) production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition.

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Decylubiquinone Chemical Structure

Decylubiquinone Chemical Structure

CAS No. : 55486-00-5

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5mg (77.53 mM * 200 μL in Ethanol) USD 140 In-stock
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10mg (77.53 mM * 400 μL in Ethanol) USD 220 In-stock
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Based on 1 publication(s) in Google Scholar

Decylubiquinone Related Antibodies

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Description

Decylubiquinone is an analog of ubiquinone (coenzyme Q10). Decylubiquinone blocks reactive oxygen species (ROS) production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition[1].

In Vitro

Decylubiquinone (dUb; 10 μm for 6 hours) exerts its effects on ROS by either inhibition of ROS production by cytochrome bc1 or that it scavenged ROS produced[1].
Decylubiquinone inhibits both the dichlorofluorescein (DCF) fluorescence increase resulting from H2O2 treatment and the DCF fluorescence increase resulting after glutathione (GSH) depletion using diethylmaleate mitochondrially generated ROS)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Decylubiquinone Related Antibodies

Cell Viability Assay[1]

Cell Line: HL60 cells transfected with bcl-2 (bcl-2) (HL60 B cells)
Concentration: 10 μM
Incubation Time: 6 hours
Result: Attenuated the ROS increase in HL60 (B) cells.
Molecular Weight

322.44

Formula

C19H30O4
CAS No.
Appearance

Liquid

Color

Yellow to brown

SMILES

O=C1C(CCCCCCCCCC)=C(C(C(OC)=C1OC)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Purity & Documentation

Purity: ≥99.0%

SDS (392 KB)

COA (242 KB)

Handling Instructions (2659 KB)
References
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Decylubiquinone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Decylubiquinone55486-00-5Reactive Oxygen SpeciesUbiquinonecoenzyme Q10reactiveoxygenspeciesROSproductionglutathionedepletionmitochondrialpermeabilitytransitionInhibitorinhibitorinhibit

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