Dehydroepiandrosterone sulfate-d₆ sodium dihydrate 

Dehydroepiandrosterone sulfate-d₆ (sodium dihydrate) is the deuterium labeled tert-Butyl N-[(1S)-1-[Methoxy(methyl)carbamoyl]-2-phenylethyl]carbamate[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[75].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

432.54

C₁₉H₂₅D₆NaO₇S

78590-17-7

Solid

White to off-white

C[C@@]12[C@]3([H])[C@](CC([2H])=C1C([2H])([2H])[C@@](C([2H])([2H])C2)([2H])OS(=O)(O[Na])=O)([H])[C@@]4([H])[C@](CC3)(C(CC4)=O)C.O.O

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.  [Content Brief]