Deoxycytidine triphosphate-¹³C₉,¹⁵N₃ dilithium  (Synonyms: dCTP-¹³C₉,¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate-¹³C₉,¹⁵N₃ dilithium)

Deoxycytidine triphosphate-¹³C₉,¹⁵N₃ (dCTP-¹³C₉,¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate-¹³C₉,¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

490.94

¹³C₉H₁₄Li₂¹⁵N₃O₁₃P₃

2056-98-6

O[13C@H]1[13CH2][13C@H]([15N]2[13C]([15N]=[13C]([15NH2])[13CH]=[13CH]2)=O)O[13C@@H]1[13CH2]OP(OP(OP(O)(O[Li])=O)(O[Li])=O)(O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. M H Tattersall, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975 Apr;5(2):191-202.  [Content Brief]

  [3]. A W Harris, et al. Effect of thymidine on the sensitivity of cultured mouse tumor cells to 1-beta-D-arabinofuranosylcytosine. Cancer Res. 1979 Feb;39(2 Pt 1):538-41.  [Content Brief]

  [4]. B A Bladergroen, et al. CTP:phosphoethanolamine cytidylyltransferase. Biochim Biophys Acta. 1997 Sep 4;1348(1-2):91-9.  [Content Brief]