1. Others Metabolic Enzyme/Protease
  2. Drug Intermediate Drug Metabolite
  3. Desacetylvinblastine

Desacetylvinblastine  (Synonyms: 4-Desacetylvinblastine; Desacetylvincaleukoblastine)

Cat. No.: HY-133005
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Desacetylvinblastine (4-Desacetylvinblastine) is the major metabolite of Vinblastine (HY-13780) and a cytotoxic agent. When used alone, desacetylvinblastine has poor anti-tumor effects, but it can exert significant anti-tumor activity when in the presence of specific conjugates.

For research use only. We do not sell to patients.

Desacetylvinblastine Chemical Structure

Desacetylvinblastine Chemical Structure

CAS No. : 3352-69-0

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Description

Desacetylvinblastine (4-Desacetylvinblastine) is the major metabolite of Vinblastine (HY-13780) and a cytotoxic agent. When used alone, desacetylvinblastine has poor anti-tumor effects, but it can exert significant anti-tumor activity when in the presence of specific conjugates[1].

Molecular Weight

768.94

Formula

C44H56N4O8

CAS No.
SMILES

CC[C@]1(O)C[C@]2([H])C[C@@](C3=C(OC)C=C(N([C@]4([H])[C@@]56[C@]7([H])[C@](C=CCN7CC6)(CC)[C@@H](O)[C@@]4(C(OC)=O)O)C)C5=C3)(C(OC)=O)C8=C(CC[N@@](C2)C1)C9=CC=CC=C9N8

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Desacetylvinblastine
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HY-133005
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