DHATS(Leu-¹³C₆,¹⁵N)PVTIPSAVST(Gly-¹³C₂,¹⁵N)HTTPLPVTDT TFA 

DHATS(Leu-¹³C₆,¹⁵N)PVTIPSAVST(Gly-¹³C₂,¹⁵N)HTTPLPVTDT (TFA) is the ¹³C and ¹⁵N labeled isotope of DHATS-PVTIPSAVST-HTTPLPVTDT (TFA)^[1].

2725.89 (free acid)

C₁₁₀¹³C₈H₁₉₁N₂₉¹⁵N₂O₄₂.xC₂HF₃O₂

Solid

White to off-white

Asp-His-Ala-Thr-Ser-Leu-Pro-Val-Thr-Ile-Pro-Ser-Ala-Val-Ser-Thr-Gly-His-Thr-Thr-Pro-Leu-Pro-Val-Thr-Asp-Thr

DHATSLPVTIPSAVSTGHTTPLPVTDT

O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C([15NH][13C@@H]([13CH2][13CH]([13CH3])[13CH3])[13C](N2[C@@H](CCC2)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@@H](C)CC)C(N3[C@@H](CCC3)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C([15NH][13CH2][13C](N[C@@H](CC4=CNC=N4)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N5[C@@H](CCC5)C(N[C@@H](CC(C)C)C(N6[C@@H](CCC6)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@H](O)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N.O=C(C(F)(F)F)O.[x]

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Russak, et sl. Impact of deuterium substitution on the pharmacokinetics of pharmaceuticals. Annals of Pharmacotherapy 53.2 (2019): 211-225.  [Content Brief]