2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease Apoptosis
  3. Reactive Oxygen Species Apoptosis
  4. Didocosahexaenoin

Didocosahexaenoin, an omega-3 derivative, is a diglyceride of DHA and can be synthesised from DHA triglycerides. Didocosahexaenoin causes significant loss of mitochondrial membrane potential and induces ROS production. Didocosahexaenoin induces apoptosis. Didocosahexaenoin induces stronger cytotoxicity than DHA in human prostate carcinoma cells.

For research use only. We do not sell to patients.

Didocosahexaenoin Chemical Structure

Didocosahexaenoin Chemical Structure

CAS No. : 124538-05-2

Size Price Stock Quantity
1 mg USD 158 Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks
5 mg   Get quote  
10 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Didocosahexaenoin Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Didocosahexaenoin, an omega-3 derivative, is a diglyceride of DHA and can be synthesised from DHA triglycerides. Didocosahexaenoin causes significant loss of mitochondrial membrane potential and induces ROS production. Didocosahexaenoin induces apoptosis. Didocosahexaenoin induces stronger cytotoxicity than DHA in human prostate carcinoma cells[1].

In Vitro

Didocosahexaenoin (10-50 μM; 96 hours) induces cell apoptosis in PC3 cells[1].
Didocosahexaenoin (1 nM-100 μM; 96 hours) induces dose-dependent cytotoxicity on human prostate cells[1].
Didocosahexaenoin (30, 50 μM; 24 hours) causes a significant fold change increase in the loss of mitochondrial membrane potential[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Didocosahexaenoin Related Antibodies

Apoptosis Analysis[1]

Cell Line: PC3 cells
Concentration: 10, 20, 30, 40, 50 μM
Incubation Time: 24, 48 hours
Result: Caused elevated levels of early apoptotic cells.
Significantly increased the level of activated caspase 3/7 for 6 h at 30 and 50 μM.

Cell Cytotoxicity Assay[1]

Cell Line: PC3, DU145, A2780 and A2780-CP70 carcinoma cells and MCF-7 and LNCaP cells
Concentration: 1 nM-100 μM
Incubation Time: 96 hours
Result: Induced dose-dependent cytotoxicity with the strongest toxicity under 10.0 μM on DU145 and PC3 cells, A2780 and A2780-CP70 with IC50 of 3.20 and 3.82 μM, 4.6, 5.53 μM, respectively.
Molecular Weight

713.04

Formula

C47H68O5
CAS No.
SMILES

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O.OCC(CO)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Didocosahexaenoin Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Didocosahexaenoin124538-05-2Reactive Oxygen SpeciesApoptosisomega-3diglycerideDHADHA triglyceridesmitochondrial membrane potentialROScytotoxicityprostate carcinomaInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Didocosahexaenoin
Cat. No.:
HY-148944
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (0 KB) Français - FR (0 KB) Deutsch - DE (0 KB) Norwegian - NO (0 KB) Español - ES (0 KB) Swedish - SV (0 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.