1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite HMG-CoA Reductase (HMGCR)
  3. Dihydromevinolin

Dihydromevinolin  (Synonyms: Lovastatin EP impurity E; 4a,5-Dihydromevinolin)

Cat. No.: HY-Z8472
Handling Instructions Technical Support

Dihydromevinolin is a potent hypocholesterolemic metabolite produced by Aspergillus terreus. Dihydromevinolin is a HMG-CoA reductase inhibitor.

For research use only. We do not sell to patients.

Dihydromevinolin Chemical Structure

Dihydromevinolin Chemical Structure

CAS No. : 77517-29-4

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Description

Dihydromevinolin is a potent hypocholesterolemic metabolite produced by Aspergillus terreus. Dihydromevinolin is a HMG-CoA reductase inhibitor[1].

IC50 & Target

Microbial Metabolite

 

Molecular Weight

406.56

Formula

C24H38O5

CAS No.
SMILES

CC[C@H](C)C(O[C@@H]1[C@@]2([H])[C@@](C[C@@H](C1)C)([H])C=C[C@@H]([C@@H]2CC[C@@H]3C[C@H](CC(O3)=O)O)C)=O

Structure Classification
Initial Source

Aspergillus terreus ATCC 20542

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Dihydromevinolin
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