DMT-dT Phosphoramidite-¹³C₁₀,¹⁵N₂ 

DMT-dT Phosphoramidite-¹³C₁₀,¹⁵N₂ is the ¹³C and ¹⁵N labeled DMT-dT Phosphoramidite[1]. DMT-dT Phosphoramidite is typically used in the synthesis of DNA[2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

756.73

C₃₀¹³C₁₀H₄₉N₂¹⁵N₂O₈P

2483830-17-5

CC(N(P(O[13C@H]1[13CH2][13C@@]([H])(O[13C@@H]1[13CH2]OC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)[15N]5[13C]([15NH][13C]([13C]([13CH3])=[13CH]5)=O)=O)OCCC#N)C(C)C)C

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. James D Thorpe, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26(41):8857-8861.  [Content Brief]