2. Anti-infection Epigenetics
  3. Parasite DNA Methyltransferase
  4. DNMT-IN-3

DNMT-IN-3 is an DNA Methyltransferase (DNMT) inhibitor, and plays an antimalarial role with IC50 of 60 nM against Plasmodium falciparum (Plasmodium). DNMT-IN-3 can be used for malaria related research.

For research use only. We do not sell to patients.

DNMT-IN-3 Chemical Structure

DNMT-IN-3 Chemical Structure

CAS No. : 1683516-27-9

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DNMT-IN-3 Related Antibodies

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Description

DNMT-IN-3 is an DNA Methyltransferase (DNMT) inhibitor, and plays an antimalarial role with IC50 of 60 nM against Plasmodium falciparum (Plasmodium). DNMT-IN-3 can be used for malaria related research[1].

IC50 & Target

Plasmodium

 

In Vitro

DNMT-IN-3 (Compound 70) (30 μM, 1 hour) makes EIF3i protein in parasite protein extracts stable from 40 °C until 52 °C in the Cellular Thermal Shift Assay (CETSA)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DNMT-IN-3 Related Antibodies
Molecular Weight

597.75

Formula

C37H39N7O
CAS No.
SMILES

C1(NCCNC2=CC=CC3=C2C=CC=C3)=C4C=CC(OCC5CCN(CC5)CCNC6=C7C=CC=CC7=NC=C6)=CC4=NC=N1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DNMT-IN-3 Related Classifications

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Keywords:

DNMT-IN-31683516-27-9ParasiteDNA MethyltransferaseDNMTsDNA MTasesantimalarialsPlasmodium falciparummalariaEIF3iInhibitorinhibitorinhibit

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