2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. DNS-8254

DNS-8254 is an oral active and brain-penetrating PDE2a inhibitor with the IC50 of 8 nM. DNS-8254 shows memory enhancing effects in a rat model.

For research use only. We do not sell to patients.

DNS-8254 Chemical Structure

DNS-8254 Chemical Structure

CAS No. : 1821107-98-5

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DNS-8254 Related Antibodies

Top Publications Citing Use of Products

View All Phosphodiesterase (PDE) Isoform Specific Products:

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PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

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Description

DNS-8254 is an oral active and brain-penetrating PDE2a inhibitor with the IC50 of 8 nM. DNS-8254 shows memory enhancing effects in a rat model[1].

Molecular Weight

454.24

Formula

C18H15BrF3N5O
CAS No.
SMILES

O=C(C1=CC=C(F)C(Br)=C1)N2CC(F)(F)C[C@H](C3=CC(C)=NC4=NC=NN34)C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DNS-8254 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DNS-82541821107-98-5DNS8254DNS 8254Phosphodiesterase (PDE)a rat model of novel object recognitionInhibitorinhibitorinhibit

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