1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugates
  3. E3 Ligase Ligand-linker Conjugate 117

E3 Ligase Ligand-linker Conjugate 117 is an E3 ubiquitinase ligand + linker conjugate (E3 Ligase Ligand-Linker Conjugates). E3 Ligase Ligand-linker Conjugate 117 can be used to synthesize PROTAC SMARCA2/4-degrader-29 (HY-162743).

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E3 Ligase Ligand-linker Conjugate 117 Chemical Structure

E3 Ligase Ligand-linker Conjugate 117 Chemical Structure

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Description

E3 Ligase Ligand-linker Conjugate 117 is an E3 ubiquitinase ligand + linker conjugate (E3 Ligase Ligand-Linker Conjugates). E3 Ligase Ligand-linker Conjugate 117 can be used to synthesize PROTAC SMARCA2/4-degrader-29 (HY-162743)[1].

Molecular Weight

612.76

Formula

C34H44N8O3

SMILES

O=C1N(C2C(NC(CC2)=O)=O)C3=CC=C([C@@H]4CC[C@H](N5CCC(C6=NC=CC(N7C8CNCC7CC8)=N6)CC5)CC4)C=C3N1C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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E3 Ligase Ligand-linker Conjugate 117 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
E3 Ligase Ligand-linker Conjugate 117
Cat. No.:
HY-159683
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