2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. E3 Ligase Ligand-linker Conjugate 91

E3 Ligase Ligand-linker Conjugate 91 is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. E3 Ligase Ligand-linker Conjugate 91 can be used as a key intermediate for the synthesis of complete PROTAC molecules.

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E3 Ligase Ligand-linker Conjugate 91 Chemical Structure

E3 Ligase Ligand-linker Conjugate 91 Chemical Structure

CAS No. : 2229713-40-8

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E3 Ligase Ligand-linker Conjugate 91 Related Antibodies

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View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Description

E3 Ligase Ligand-linker Conjugate 91 is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. E3 Ligase Ligand-linker Conjugate 91 can be used as a key intermediate for the synthesis of complete PROTAC molecules.

IC50 & Target

von Hippel-Lindau (VHL)[1]
Molecular Weight

700.89

Formula

C35H52N6O7S
CAS No.
SMILES

O=C([C@H]1N(C[C@@H](C1)O)C([C@H](C(C)(C)C)NC(COCCN2CCN(CC2)C(OC(C)(C)C)=O)=O)=O)NCC(C=C3)=CC=C3C(SC=N4)=C4C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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E3 Ligase Ligand-linker Conjugate 91 Related Classifications

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Help & FAQs
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E3 Ligase Ligand-linker Conjugate 912229713-40-8E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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