2. Apoptosis Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. Apoptosis EGFR
  4. EGFR-IN-153

EGFR-IN-153 (Compound 5l) is an EGFR inhibitor. EGFR-IN-153 can inhibit the proliferation (IC50: 0.73 μM) and induce apoptosis of MDA-MB-231 cell. EGFR-IN-153 can be used for the research of breast cancer.

For research use only. We do not sell to patients.

EGFR-IN-153 Chemical Structure

EGFR-IN-153 Chemical Structure

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EGFR-IN-153 Related Antibodies

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Description

EGFR-IN-153 (Compound 5l) is an EGFR inhibitor. EGFR-IN-153 can inhibit the proliferation (IC50: 0.73 μM) and induce apoptosis of MDA-MB-231 cell. EGFR-IN-153 can be used for the research of breast cancer[1].

Molecular Weight

520.99

Formula

C25H21ClN6O3S
SMILES

N#CC1CCCN1C(CN2C(/C(C3=C2C=CC(Cl)=C3)=N\NC4=NC=C(C5=CC=C(OC)C=C5)S4)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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EGFR-IN-153 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR-IN-153ApoptosisEGFREpidermal growth factor receptorErbB-1HER1MDA-MB-231L929Inhibitorinhibitorinhibit

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