2. PROTAC
  3. PROTAC Linkers
  4. endo-BCN-PEG2-alcohol

endo-BCN-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. endo-BCN-PEG2-alcohol is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

For research use only. We do not sell to patients.

endo-BCN-PEG2-alcohol Chemical Structure

endo-BCN-PEG2-alcohol Chemical Structure

CAS No. : 1807501-85-4

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Based on 1 publication(s) in Google Scholar

endo-BCN-PEG2-alcohol Related Antibodies

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Description

endo-BCN-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-PEG2-alcohol is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

endo-BCN-PEG2-alcohol Related Antibodies
Molecular Weight

325.40

Formula

C17H27NO5
CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

OCCOCCOCCNC(OCC1C2([H])C1([H])CCC#CCC2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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endo-BCN-PEG2-alcohol Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

endo-BCN-PEG2-alcohol1807501-85-4PROTAC LinkersInhibitorinhibitorinhibit

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