2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. Eprociclovir

Eprociclovir is an antiviral drug with nucleoside analogues. The triphosphate form of Eprociclovir is converted into the active form within virus-infected cells by the virus and possible cellular enzymes, including the viral thymidine kinase, thereby inhibiting the activity of the viral DNA polymerase. The primary activity of Eprociclovir is against herpes viruses, including but not limited to cytomegalovirus (CMV) and herpes simplex virus (HSV). Eprociclovir can be used in studies interfered with by sensitive viruses.

For research use only. We do not sell to patients.

Eprociclovir Chemical Structure

Eprociclovir Chemical Structure

CAS No. : 145512-85-2

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Other Forms of Eprociclovir:

Eprociclovir Related Antibodies

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Description

Eprociclovir is an antiviral drug with nucleoside analogues. The triphosphate form of Eprociclovir is converted into the active form within virus-infected cells by the virus and possible cellular enzymes, including the viral thymidine kinase, thereby inhibiting the activity of the viral DNA polymerase. The primary activity of Eprociclovir is against herpes viruses, including but not limited to cytomegalovirus (CMV) and herpes simplex virus (HSV). Eprociclovir can be used in studies interfered with by sensitive viruses[1].

Cellular Effect
Cell Line Type Value Description References
CCRF-CEM IC50
> 100 μg/mL
Compound: 3a
Inhibitory activity against 1RF strain of HIV-1 by plaque reduction assay in CEM cells
Inhibitory activity against 1RF strain of HIV-1 by plaque reduction assay in CEM cells
[PMID: 9548818]
HEL IC50
0.67 μg/mL
Compound: 1
Tested for inhibitory activity against Varicella zoster virus(VZV) by plaque reduction assay using HEL cells
Tested for inhibitory activity against Varicella zoster virus(VZV) by plaque reduction assay using HEL cells
[PMID: 10649983]
HFF IC50
0.2 μg/mL
Compound: 3a
Inhibitory activity against DM625 strain of zoster virus(VZV) by plaque reduction assay in HFF cells
Inhibitory activity against DM625 strain of zoster virus(VZV) by plaque reduction assay in HFF cells
[PMID: 9548818]
Vero IC50
0.02 μg/mL
Compound: 3a
Inhibition of Tomioka strain of herpes simplex virus( Tomioka strain of HSV-1) by quantitative CPE reduction assay in vero cells
Inhibition of Tomioka strain of herpes simplex virus( Tomioka strain of HSV-1) by quantitative CPE reduction assay in vero cells
[PMID: 9548818]
Molecular Weight

265.27

Formula

C11H15N5O3
CAS No.
SMILES

OC[C@@]1([C@@H](C1)CO)CN2C3=C(C(N=C(N3)N)=O)N=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Eprociclovir Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eprociclovir145512-85-2A-5021A5021A 5021DNA/RNA SynthesisNucleoside analoguesDNA polymeraseherpes virussensitive virusInhibitorinhibitorinhibit

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