2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. ER degrader 6

ER degrader 6 (compound 35s) is a potent Estrogen Receptor (ER)α degrader. ER degrader 6 disrupts the microtubule network by restraining tubulin polymerization. ER degrader 6 suppresses tumor growth without noticeable poisonousness.

For research use only. We do not sell to patients.

ER degrader 6 Chemical Structure

ER degrader 6 Chemical Structure

CAS No. : 2922929-62-0

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ER degrader 6 Related Antibodies

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

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Description

ER degrader 6 (compound 35s) is a potent Estrogen Receptor (ER)α degrader. ER degrader 6 disrupts the microtubule network by restraining tubulin polymerization. ER degrader 6 suppresses tumor growth without noticeable poisonousness[1].

IC50 & Target

ERα

 

In Vitro

ER degrader 6 (compound 35s) exhibits antiproliferative and ERα degradation activity in multiple ERα-positive breast cancer (BC) cell lines bearing either wild-type or mutant ERα[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ER degrader 6 Related Antibodies
Molecular Weight

682.66

Formula

C33H34FN3O5SSe
CAS No.
SMILES

O=C(CCCCC[Se]C#N)NC1=CC=C(C2=C(C3=CC=C(O)C=C3)[C@H]4CC(S(N(CC)C5=C(F)C=CC=C5)(=O)=O)[C@@H]2O4)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ER degrader 6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ER degrader 62922929-62-0ER degrader6ER degrader-6Estrogen Receptor/ERRInhibitorinhibitorinhibit

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ER degrader 6
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