2. NF-κB Metabolic Enzyme/Protease Neuronal Signaling Membrane Transporter/Ion Channel Immunology/Inflammation
  3. NF-κB Glutathione S-transferase Calcium Channel NO Synthase
  4. Ethacrynic acid sodium

Ethacrynic acid sodium  (Synonyms: Etacrynic acid sodium; Sodium etacrynate)

Cat. No.: HY-B1640A
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Ethacrynic acid (Etacrynic acid sodium) sodium is a diuretic. Ethacrynic acid sodium is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid sodium is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid sodium also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid sodium has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice.

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Ethacrynic acid sodium Chemical Structure

Ethacrynic acid sodium Chemical Structure

CAS No. : 6500-81-8

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Ethacrynic acid sodium Related Antibodies

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Description

Ethacrynic acid (Etacrynic acid sodium) sodium is a diuretic. Ethacrynic acid sodium is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid sodium is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid sodium also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid sodium has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice[1][2][3][4].

Clinical Trial
Molecular Weight

325.12

Formula

C13H11Cl2NaO4
CAS No.
SMILES

O=C(O[Na])COC1=CC=C(C(C(CC)=C)=O)C(Cl)=C1Cl
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Ethacrynic acid sodium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ethacrynic acid6500-81-8Etacrynic acid Sodium etacrynateNF-κBGlutathione S-transferaseCalcium ChannelNO SynthaseNuclear factor-κBNuclear factor-kappaBGlutathione transferasesGSTsCa2+ channelsCa channelsNitric oxide synthasesNOSInhibitorinhibitorinhibit

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