2. Protein Tyrosine Kinase/RTK
  3. FAK
  4. FAK inhibitor 6

Compound 26F not only optimized the effective inhibitory enzyme (ic50= 28.2 nm), but also showed relatively less cytotoxicity (ic50= 3.32 μ M) And induced MDA-MB-231 cell apoptosis in a dose-dependent manner, effectively blocking MDA-MB-231 cells in g0/g1 phase.

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FAK inhibitor 6 Chemical Structure

FAK inhibitor 6 Chemical Structure

CAS No. : 2410056-27-6

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FAK inhibitor 6 Related Antibodies

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Description

Compound 26F not only optimized the effective inhibitory enzyme (ic50= 28.2 nm), but also showed relatively less cytotoxicity (ic50= 3.32 μ M) And induced MDA-MB-231 cell apoptosis in a dose-dependent manner, effectively blocking MDA-MB-231 cells in g0/g1 phase.

Molecular Weight

477.55

Formula

C25H24FN5O2S
CAS No.
SMILES

COC1=CC=CC=C1C2=CSC3=CN=C(N=C32)NC4=CC(F)=C(C=C4)C(NC5CCNCC5)=O
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FAK inhibitor 6 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FAK inhibitor 62410056-27-6FAK inhibitor6FAK inhibitor-6FAKPTK2 protein tyrosine kinase 2PTK2Focal adhesion kinaseInhibitorinhibitorinhibit

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