Femoxetine hydrochloride (Synonyms: FG4963)

Cat. No.: HY-106644A: FAQs
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Femoxetine hydrochloride is a serotonin (5-HT) inhibitor with antidepressant properties. Femoxetine hydrochloride increases serotonin levels in the brain by preventing serotonin from being reabsorbed by nerve cells, resulting in increased concentrations of the neurotransmitter in the synaptic gap, which enhances serotonin signaling. Femoxetine hydrochloride can be used to study the role of serotonin in depression and other emotional disorders, and how 5-HT reuptake inhibitors affect mood and behavior.

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Femoxetine hydrochloride Chemical Structure

CAS No. : 56222-04-9

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Other Forms of Femoxetine hydrochloride:

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5-HT₁ Receptor 5-HT₂ Receptor 5-HT₃ Receptor 5-HT₄ Receptor 5-HT₅ Receptor 5-HT₆ Receptor 5-HT₇ Receptor 5-HT Receptor

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Description	Femoxetine hydrochloride is a serotonin (5-HT) inhibitor with antidepressant properties. Femoxetine hydrochloride increases serotonin levels in the brain by preventing serotonin from being reabsorbed by nerve cells, resulting in increased concentrations of the neurotransmitter in the synaptic gap, which enhances serotonin signaling. Femoxetine hydrochloride can be used to study the role of serotonin in depression and other emotional disorders, and how 5-HT reuptake inhibitors affect mood and behavior^[1]^[2].
Molecular Weight	347.88
Formula	C₂₀H₂₆ClNO₂
CAS No.	56222-04-9
SMILES	COC(C=C1)=CC=C1OC[C@@H]2[C@@H](C3=CC=CC=C3)CCN(C2)C.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (267 KB) Handling Instructions (2659 KB)
References	[1]. Bechgaard E, et al. Hepatic elimination of femoxetine in pig[J]. Acta Pharmacologica et Toxicologica, 1983, 52(1): 1-7. [Content Brief] [2]. Lund J, et al. Pharmacokinetics of femoxetine in man[J]. Acta Pharmacologica et Toxicologica, 1979, 44(3): 177-184. [Content Brief]

Femoxetine hydrochloride Related Classifications

Neurological Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Femoxetine56222-04-9FG4963FG 4963FG-49635-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptor5HTNeurotransmitterDepressionReuptake inhibitorInhibitorinhibitorinhibit

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