2. Protein Tyrosine Kinase/RTK
  3. FGFR
  4. FGFR-IN-6

FGFR-IN-6 (Compound 5) is a FGFR inhibitor. FGFR-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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FGFR-IN-6 Chemical Structure

FGFR-IN-6 Chemical Structure

CAS No. : 2762955-18-8

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FGFR-IN-6 Related Antibodies

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Description

FGFR-IN-6 (Compound 5) is a FGFR inhibitor[1]. FGFR-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

In Vitro

FGFR-IN-6 (Compound 5) shows antiproliferation activity with IC50 values of 0.5-5 nM against BaF3-Tel-FGFR2WT and various mutant FGFR2 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

FGFR-IN-6 Related Antibodies
Molecular Weight

430.46

Formula

C23H22N6O3
CAS No.
SMILES

C=CC(N1CC[C@@H](C1)N2N=C(C(C(N)=O)=C2N)C#CC3=CC4=C(OC(C5CC5)=N4)C=C3)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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FGFR-IN-6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FGFR-IN-62762955-18-8FGFRFibroblast growth factor receptorBaF3FGFR3V555McancerInhibitorinhibitorinhibit

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HY-147621
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