1. Metabolic Enzyme/Protease
  2. NADPH Oxidase
  3. Fluoflavine

Fluoflavine  (Synonyms: ML-090)

Cat. No.: HY-126195 Purity: 99.41%
COA Handling Instructions

Fluoflavine (ML-090) is a selective NOX1 inhibitor with an IC50 of 90 nM. Fluoflavine has >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50>10 μM). ML-090 has an IC50 of 360 nM in HEK293 cells.

For research use only. We do not sell to patients.

Fluoflavine Chemical Structure

Fluoflavine Chemical Structure

CAS No. : 531-46-4

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Description

Fluoflavine (ML-090) is a selective NOX1 inhibitor with an IC50 of 90 nM. Fluoflavine has >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50>10 μM). ML-090 has an IC50 of 360 nM in HEK293 cells[1].

IC50 & Target

NOX1

 

Molecular Weight

234.26

Formula

C14H10N4

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

C1(N2)=NC3=C(C=CC=C3)NC1=NC4=C2C=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.41%

References
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Fluoflavine Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Fluoflavine
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