2. PROTAC
  3. PROTAC Linkers
  4. FmocNH-PEG4-t-butyl ester

FmocNH-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

FmocNH-PEG4-t-butyl ester Chemical Structure

FmocNH-PEG4-t-butyl ester Chemical Structure

CAS No. : 2148295-94-5

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FmocNH-PEG4-t-butyl ester Related Antibodies

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Description

FmocNH-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

FmocNH-PEG4-t-butyl ester Related Antibodies
Molecular Weight

543.65

Formula

C30H41NO8
CAS No.
Appearance

Liquid (Density: 1.145 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCC(OC(C)(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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FmocNH-PEG4-t-butyl ester Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FmocNH-PEG4-t-butyl ester2148295-94-5PROTAC LinkersInhibitorinhibitorinhibit

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