2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. Friedelin (Standard)

Friedelin (Standard) is the analytical standard of Friedelin. This product is intended for research and analytical applications. Friedelin is isolated from isolated from the leaves of Maytenus ilicifolia(Mart). Friedelin is a noncompetitive inhibitor of CYP3A4 with IC50 and Kivalues of 10.79 ?μM and 6.16? μM, respectively. Friedelin is also a competitive inhibitor of CYP2E1 with IC50 and Ki values of 22.54? μM and 18.02 μM, respectively.

For research use only. We do not sell to patients.

Friedelin (Standard) Chemical Structure

Friedelin (Standard) Chemical Structure

CAS No. : 559-74-0

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Description
Molecular Weight

426.72

Formula

C30H50O
CAS No.
SMILES

C[C@@]12[C@]([C@@]3([H])[C@](C)(CCC(C)(C)C3)CC1)(CC[C@]4(C)[C@]2([H])CC[C@@]([C@H]5C)(C)[C@@]4([H])CCC5=O)C
Structure Classification
Initial Source
Storage

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Purity & Documentation
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Friedelin (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Friedelin (Standard)559-74-0Cytochrome P450CYPsInhibitorinhibitorinhibit

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