fStAx-35R TFA

Cat. No.: HY-P10392AF: FAQs
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fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research.

For research use only. We do not sell to patients.

fStAx-35R TFA Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 550	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 1400	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Description	fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research^[1].
Molecular Weight	2885.36 (free base)
Formula	C₁₃₆H₁₉₈N₄₂O₂₇S.xC₂HF₂O₂
Sequence Shortening	FITC-PEG1-RRWPR-S5-ILD-S5-HVRRVWR-NH2
SMILES	O=C([C@H](CCCNC(N)=N)NC(COCCOCCNC(NC1=CC2=C(C3(OC2=O)C4=C(OC5=C3C=CC(O)=C5)C=C(O)C=C4)C=C1)=S)=O)N[C@@H](CCCNC(N)=N)C(N[C@@H](CC6=CNC7=C6C=CC=C7)C(N8CCC[C@H]8C(N[C@@H](CCCNC(N)=N)C(N[C@](C)(C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@H]9CC(O)=O)=O)=O)=O)CCC/C=C/CCC[C@@](C)(C(N[C@@H](CC%10=CN=CN%10)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC%11=CNC%12=C%11C=CC=C%12)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)NC9=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility	In Vitro: DMSO : ≥ 100 mg/mL "≥" means soluble, but saturation unknown. Molarity Calculator Dilution Calculator Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Mass = Concentration × Volume × Molecular Weight Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final) This equation is commonly abbreviated as: C₁V₁ = C₂V₂ Concentration _(start) C1 × Volume _(start) V1 = Concentration _(final) C2 × Volume _(final) V2 In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kg Animal weight (per animal) g Dosing volume (per animal) μL Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Calculation results: Working solution concentration: mg/mL
Purity & Documentation	Data Sheet (270 KB) Handling Instructions (2659 KB)
References	[1]. Cui HK, et al., Design of stapled α-helical peptides to specifically activate Wnt/β-catenin signaling. Cell Res. 2013 Apr;23(4):581-4. [Content Brief]

fStAx-35R TFA Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

fStAx-35Rβ-cateninBeta cateninInhibitorinhibitorinhibit

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fStAx-35R TFA

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