fStAx-35R TFA

Cat. No.: HY-P10392AF Purity: 97.35%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research.

For research use only. We do not sell to patients.

fStAx-35R TFA Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 550	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 1400	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

2885.36 (free base)

Formula

C₁₃₆H₁₉₈N₄₂O₂₇S.xC₂HF₂O₂

Appearance

Solid

Color

Light yellow to yellow

Sequence Shortening

FITC-PEG1-RRWPR-S5-ILD-S5-HVRRVWR-NH2

SMILES

O=C([C@H](CCCNC(N)=N)NC(COCCOCCNC(NC1=CC2=C(C3(OC2=O)C4=C(OC5=C3C=CC(O)=C5)C=C(O)C=C4)C=C1)=S)=O)N[C@@H](CCCNC(N)=N)C(N[C@@H](CC6=CNC7=C6C=CC=C7)C(N8CCC[C@H]8C(N[C@@H](CCCNC(N)=N)C(N[C@](C)(C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@H]9CC(O)=O)=O)=O)=O)CCC/C=C/CCC[C@@](C)(C(N[C@@H](CC%10=CN=CN%10)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC%11=CNC%12=C%11C=CC=C%12)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)NC9=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL

*"≥" means soluble, but saturation unknown.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 97.35%

Select Batch:

Data Sheet (270 KB) SDS (252 KB)

COA (253 KB) RP-HPLC (113 KB) MS (223 KB)

Handling Instructions (2659 KB)

References

[1]. Cui HK, et al., Design of stapled α-helical peptides to specifically activate Wnt/β-catenin signaling. Cell Res. 2013 Apr;23(4):581-4. [Content Brief]

fStAx-35R TFA Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

fStAx-35Rβ-cateninBeta cateninInhibitorinhibitorinhibit

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