Ganglioside GD3 diammonium

Cat. No.: HY-131139A Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Ganglioside GD3 diammonium is an acidic glycosphingolipid. Ganglioside GD3 diammonium inhibits the proliferation of cancer cells, affects the opening of the mitochondrial permeability transition pore (PTPC), induces apoptosis and activates caspase family. Ganglioside GD3 diammonium can be used in research about cancer and neurodegenerative diseases.

For research use only. We do not sell to patients.

Ganglioside GD3 diammonium Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 248	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 620	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

Other Forms of Ganglioside GD3 diammonium:

Ganglioside GD3 disodium salt Get quote

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Biological Activity
Purity & Documentation
References
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Description	Ganglioside GD3 diammonium is an acidic glycosphingolipid. Ganglioside GD3 diammonium inhibits the proliferation of cancer cells, affects the opening of the mitochondrial permeability transition pore (PTPC), induces apoptosis and activates caspase family. Ganglioside GD3 diammonium can be used in research about cancer and neurodegenerative diseases^[1].
In Vitro	Ganglioside GD3 diammonium is highly expressed in melanomas in comparison with melanocytes, is exclusively expressed in the early developmental stage of the fetal brain, and is highly expressed in activated T lymphocytes and in T cell malignant tumor cells suggest that GD3 is involved in tumor phenotypes, such as enhanced proliferation and frequent metastasis^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Ganglioside GD3 diammonium Related Antibodies
Molecular Weight	1506.81
Formula	C₇₀H₁₃₁N₅O₂₉
Appearance	Solid
Color	White to off-white
SMILES	OC([C@](O[C@@]([C@@H]1NC(C)=O)([H])[C@H](O)[C@@H](CO)O[C@@](O[C@@]([C@@H]2NC(C)=O)([H])[C@H](O)[C@H](O)CO)(C[C@@H]2O)C(O)=O)(C[C@@H]1O)O[C@@H]([C@H]([C@H]3CO)O)[C@H]([C@@H](O3)O[C@@H]([C@@H]([C@H]4O)O)[C@H](O[C@H]4OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCC)=O)CO)O)=O.N.N
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation	Purity: ≥98.0% Select Batch: Data Sheet (278 KB) SDS (252 KB) COA (267 KB) Handling Instructions (2659 KB)
References	[1]. Malisan F, et al., GD3 ganglioside and apoptosis. Biochim Biophys Acta. 2002 Dec 30;1585(2-3):179-87. [Content Brief] [2]. Kazunori Hamamura, et al. Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11041-6. [Content Brief]