2. Apoptosis
  3. Apoptosis
  4. Ganoderic acid R

Ganoderic acid R is a potent anticancer agent. Ganoderic acid R inhibits the growth by inducing apoptosis on tumor cell line. Ganoderic acid R possesses significant cytotoxicity on a multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and a sensitive tumor cell line (KB-A-1).

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Ganoderic acid R Chemical Structure

Ganoderic acid R Chemical Structure

CAS No. : 103963-39-9

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Ganoderic acid R Related Antibodies

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Description

Ganoderic acid R is a potent anticancer agent. Ganoderic acid R inhibits the growth by inducing apoptosis on tumor cell line. Ganoderic acid R possesses significant cytotoxicity on a multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and a sensitive tumor cell line (KB-A-1)[1].

In Vitro

Ganoderic acid R (0-50 µg/mL, 48 h) inhibit the growth by inducing apoptosis on tumor cell lines at the concentrations that more than 20 µg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ganoderic acid R Related Antibodies

Apoptosis Analysis[1]

Cell Line: KB-A-1/Dox cells
Concentration: 0, 25, 50 μg/mL
Incubation Time: 48 h
Result: Induced the cellular apoptosis, the number of apoptotic cells was increased from 35% to 90% during 48 h.
Molecular Weight

554.76

Formula

C34H50O6
CAS No.
SMILES

C[C@@]12C3=CC[C@](C)([C@@](CC4)([H])[C@H](C)[C@@H](OC(C)=O)C/C=C(C)/C(O)=O)[C@]4(C)C3=CC[C@@]1([H])C(C)([C@@H](CC2)OC(C)=O)C
Structure Classification
Initial Source

glossy ganoderma
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ganoderic acid R Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ganoderic acid R103963-39-9ApoptosisAnticancerKB-A-1/Dox cellsKB-A-1 cellsGanoderic acidInhibitorinhibitorinhibit

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