2. Gene
  3. SIGLEC14 - sialic acid binding Ig like lectin 14 Gene

SIGLEC14 - sialic acid binding Ig like lectin 14 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 100049587 | Gene type: protein coding

About SIGLEC14

Cytogenetic location: 19q13.41 Genomic coordinates (GRCh38): 19:51,639,478-51,646,825 (from NCBI)

This gene has 2 transcripts (splice variants), 139 orthologues and 16 paralogues. Biased expression in spleen (RPKM 13.9), appendix (RPKM 9.2) and 7 other tissues.

Summary

Predicted to enable sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to be located in ficolin-1-rich granule membrane and tertiary granule membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SIGLEC14 Products(1)

mRNA Protein Name
NM_001098612.3 NP_001092082.1 sialic acid-binding Ig-like lectin 14 precursor

SIGLEC14 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (25 - 138)

ig

ig: Immunoglobulin domain (160 - 215)

Ig_2

Ig_2: Immunoglobulin domain (262 - 335)

  • 0
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  • 396 a.a.
Protein Preferred Names Protein Names

sialic acid-binding Ig-like lectin 14

siglec-14

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12901 SIGLEC14 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SIGLEC14 MGD MGI:2681107