UST - uronyl 2-sulfotransferase Gene

Homo sapiens

Also known as 2OST

Gene ID: 10090 | Gene type: protein coding

About UST

Cytogenetic location: 6q25.1 Genomic coordinates (GRCh38): 6:148,747,030-149,076,990 (from NCBI)

This gene has 3 transcripts (splice variants), 218 orthologues and 1 paralogue. Broad expression in thyroid (RPKM 10.7), adrenal (RPKM 4.5) and 21 other tissues.

Summary

Uronyl 2-sulfotransferase transfers sulfate to the 2-position of uronyl residues, such as iduronyl residues in dermatan sulfate and glucuronyl residues in chondroitin sulfate (Kobayashi et al., 1999 [PubMed 10187838]).[supplied by OMIM, Mar 2008]

UST Products(1)

mRNA	Protein	Name
NM_005715.3	NP_005706.1	uronyl 2-sulfotransferase

UST Protein Structure

Sulfotransfer_2

0
100
200
300
406 a.a.

Protein Preferred Names

Protein Names

uronyl 2-sulfotransferase

dermatan/chondroitin sulfate 2-sulfotransferase

Related Diseases

Diseases

Alias

Breast Pericanalicular Fibroadenoma

Pericanalicular Fibroadenoma

Pericanalicular Fibroadenoma Of Breast

Acute Retinal Necrosis Syndrome

Acute Retinal Necrosis

Retinal Necrosis Syndrome, Acute

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15573	UST Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	UST	RGD	RGD:1304743
Macaca mulatta	UST	VGNC	VGNC:79067
Bos taurus	UST	VGNC	VGNC:107018
Felis catus	UST	VGNC	VGNC:66900
Mus musculus	UST	MGD	MGI:2442406
Canis familiaris	UST	VGNC	VGNC:48207
Others	UST	NCBI

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