Avpr1b - arginine vasopressin receptor 1B Gene

Rattus norvegicus

Gene ID: 100909648 | Gene type: protein coding

About Avpr1b

Primary_assembly 13: 43,046,267-43,057,792 forward strand.mRatBN7.2:CM026986.1

This gene has 1 transcript (splice variant), 132 orthologues, 16 paralogues and is associated with 12 phenotypes. Biased expression in Brain (RPKM 1.5), Heart (RPKM .2) and 2 other tissues.

Avpr1b Products(1)

mRNA	Protein	Name
NM_001289800.1	NP_001276729.1	vasopressin V1b receptor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	19047484	RGD
enables peptide hormone binding	IDA IDA: Inferred from direct assay	19047484	RGD
enables peptide hormone binding	IMP IMP: Inferred from mutant phenotype	7624319	RGD
enables vasopressin receptor activity	IDA IDA: Inferred from direct assay	19047484	RGD
enables vasopressin receptor activity	IMP IMP: Inferred from mutant phenotype	7624319	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in G protein-coupled receptor signaling pathway	IDA IDA: Inferred from direct assay	19047484	RGD
involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IDA IDA: Inferred from direct assay	19047484	RGD
involved in positive regulation of cellular pH reduction	IMP IMP: Inferred from mutant phenotype	17762181	RGD
involved in positive regulation of cytosolic calcium ion concentration	IMP IMP: Inferred from mutant phenotype	17877638	RGD
involved in positive regulation of glutamate secretion	IMP IMP: Inferred from mutant phenotype	17877638	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in dendrite	IDA IDA: Inferred from direct assay	11250948	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Avpr1b Protein Structure

7tmA_V1bR

DUF1856

0
100
200
300
421 a.a.

Protein Preferred Names

Protein Names

vasopressin V1b receptor

AVPR V1b	AVPR V3
V1bR	antidiuretic hormone receptor 1b
vasopressin V3 receptor

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P0049A	Argipressin diacetate		/	Unkown

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01284	AVPR1B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS01285	Avpr1b Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS01286	Avpr1b Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Avpr1b	NCBI	NCBI:553

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