2. Gene
  3. Ano10 - anoctamin 10 Gene

Ano10 - anoctamin 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tmem16k

Gene ID: 102566 | Gene type: protein coding

About Ano10

Summary

This gene encodes a member of the anoctamin family, which in mammals is comprised of 10 members. Anoctamin proteins are proposed to have eight transmembrane domains with both termini facing the cytoplasm and a C-terminal domain of unknown function. While some members have been characterized as calcium-activated chloride channels, this protein is reported to inhibit anion conductance. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Dec 2012]

Ano10 Products(2)

mRNA Protein Name
NM_001271873.1 NP_001258802.1 anoctamin-10 isoform 2
NM_133979.3 NP_598740.1 anoctamin-10 isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
NOT enables intracellularly calcium-gated chloride channel activity IDA
IDA: Inferred from direct assay
23532839 MGI
NOT enables phospholipid scramblase activity IDA
IDA: Inferred from direct assay
23532839 MGI
Cellular Component GO Annotation Evidence Reference Source
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
20056604 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
20056604 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

anoctamin-10

transmembrane protein 16K

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16254 Ano10 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00741 ANO10 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ano10 NCBI NCBI:55129