1. Gene
  2. ADAM29 - ADAM metallopeptidase domain 29 Gene

ADAM29 - ADAM metallopeptidase domain 29 Gene

Homo sapiens

Also known as CT73; svph1

Gene ID: 11086 | Gene type: protein coding

About ADAM29

Cytogenetic location: 4q34.1 Genomic coordinates (GRCh38): 4:174,918,358-174,978,180 (from NCBI)

This gene has 14 transcripts (splice variants), 416 orthologues and 20 paralogues. Restricted expression toward testis (RPKM 20.8).

Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is highly expressed in testis and may be involved in human spermatogenesis. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]

ADAM29 Products(7)

mRNA Protein Name
NM_001130703.1 NP_001124175.1 disintegrin and metalloproteinase domain-containing protein 29 preproprotein
NM_001130704.1 NP_001124176.1 disintegrin and metalloproteinase domain-containing protein 29 preproprotein
NM_001130705.1 NP_001124177.1 disintegrin and metalloproteinase domain-containing protein 29 preproprotein
NM_001278125.1 NP_001265054.1 disintegrin and metalloproteinase domain-containing protein 29 preproprotein
NM_001278126.1 NP_001265055.1 disintegrin and metalloproteinase domain-containing protein 29 preproprotein
NM_001278127.1 NP_001265056.1 disintegrin and metalloproteinase domain-containing protein 29 preproprotein
NM_014269.4 NP_055084.3 disintegrin and metalloproteinase domain-containing protein 29 preproprotein

ADAM29 Protein Structure

Pep_M12B_propep

Pep_M12B_propep: Reprolysin family propeptide (32 - 150)

Reprolysin

Reprolysin: Reprolysin (M12B) family zinc metalloprotease (198 - 387)

Disintegrin

Disintegrin: Disintegrin (406 - 480)

ADAM_CR

ADAM_CR: ADAM cysteine-rich (483 - 598)

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  • 600
  • 820 a.a.
Protein Preferred Names Protein Names

disintegrin and metalloproteinase domain-containing protein 29

a disintegrin and metalloproteinase domain 29

Related Diseases

Diseases Alias
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris ADAM29 VGNC VGNC:37583
Rattus norvegicus ADAM29 RGD RGD:1309066
Mus musculus ADAM29 MGD MGI:2676326
Macaca mulatta ADAM29 VGNC VGNC:106537
Others ADAM29 NCBI