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  2. Adora2a - adenosine A2a receptor Gene

Adora2a - adenosine A2a receptor Gene

Mus musculus

Also known as A2aR; A2AAR; AA2AR; ARA2A

Gene ID: 11540 | Gene type: protein coding

About Adora2a

Chromosome 10: 75,152,711-75,170,618 forward strand.GRCm39:CM001003.3

This gene has 4 transcripts (splice variants), 263 orthologues, 3 paralogues and is associated with 42 phenotypes. Broad expression in thymus adult (RPKM 8.8), spleen adult (RPKM 8.) and 26 other tissues.

Summary

Enables G protein-coupled Adenosine Receptor activity. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; chemical synaptic transmission; and positive regulation of cell communication. Located in plasma membrane. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; intestine; and liver and biliary system. Used to study myopia and primary pulmonary hypertension. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ADORA2A (adenosine A2a receptor). [provided by Alliance of Genome Resources, Apr 2022]

Adora2a Products(6)

mRNA Protein Name
NM_009630.3 NP_033760.2 adenosine receptor A2a
NM_001331095.1 NP_001318024.1 adenosine receptor A2a
NM_001331096.1 NP_001318025.1 adenosine receptor A2a
NM_001331095.1 NP_001318024.1 adenosine receptor A2a
NM_001331096.1 NP_001318025.1 adenosine receptor A2a
NM_009630.3 NP_033760.2 adenosine receptor A2a

Adora2a Protein Structure

7tmA_Adenosine_R_A2A

7tmA_Adenosine_R_A2A: cd15068 (3 - 293)

7tmA_Adenosine_R_A2A

7tmA_Adenosine_R_A2A: cd15068 (4 - 30)

7tmA_Adenosine_R_A2A

7tmA_Adenosine_R_A2A: cd15068 (37 - 64)

7tmA_Adenosine_R_A2A

7tmA_Adenosine_R_A2A: cd15068 (73 - 103)

7tmA_Adenosine_R_A2A

7tmA_Adenosine_R_A2A: cd15068 (117 - 135)

7tmA_Adenosine_R_A2A

7tmA_Adenosine_R_A2A: cd15068 (168 - 198)

7tmA_Adenosine_R_A2A

7tmA_Adenosine_R_A2A: cd15068 (220 - 250)

7tmA_Adenosine_R_A2A

7tmA_Adenosine_R_A2A: cd15068 (261 - 286)

  • 0
  • 100
  • 200
  • 300
  • 410 a.a.
Protein Preferred Names Protein Names

adenosine receptor A2a

Orthologs Information

Species Symbol Source ID
Homo sapiens Adora2a NCBI NCBI:135