Adora3 - adenosine A3 receptor Gene

Mus musculus

Also known as A3R; A3AR; AA3R; ARA3; Gpcr2

Gene ID: 11542 | Gene type: protein coding

About Adora3

Chromosome 3: 105,778,174-105,816,242 forward strand.GRCm39:CM000996.3

This gene has 3 transcripts (splice variants), 272 orthologues, 3 paralogues and is associated with 15 phenotypes. Biased expression in testis adult (RPKM 3.8), mammary gland adult (RPKM 1.) and 14 other tissues.

Summary

This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. This gene shares its 3' terminal exon with a transcript variant from overlapping GeneID:69296, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014]

Adora3 Products(1)

mRNA	Protein	Name
NM_009631.4	NP_033761.2	adenosine receptor A3

Adora3 Protein Structure

7tmA_Adenosine_R_A3

0
100
200
300
319 a.a.

Protein Preferred Names

Protein Names

adenosine receptor A3

G-protein coupled receptor 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00400	ADORA3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS00401	Adora3 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS00402	ADORA3 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Adora3	NCBI	NCBI:140

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