2. Gene
  3. Casp12 - caspase 12 Gene

Casp12 - caspase 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 12364 | Gene type: protein coding

About Casp12

Chromosome 9: 5,345,430-5,373,032 forward strand.GRCm39:CM001002.3

This gene has 5 transcripts (splice variants), 273 orthologues, 11 paralogues and is associated with 9 phenotypes. Biased expression in bladder adult (RPKM 12.1), subcutaneous fat pad adult (RPKM 1.5) and 5 other tissues.

Summary

Enables cysteine-type endopeptidase activity. Involved in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and self proteolysis. Acts upstream of or within apoptotic process and endoplasmic reticulum unfolded protein response. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human CASP12 (Caspase 12 (gene/pseudogene)). [provided by Alliance of Genome Resources, Apr 2022]

Casp12 Products(1)

mRNA Protein Name
NM_009808.4 NP_033938.3 caspase-12

Casp12 Protein Structure

CARD_CASP1-like

CARD_CASP1-like: cd08325 (5 - 87)

CASc

CASc: smart00115 (165 - 416)

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  • 419 a.a.
Protein Preferred Names Protein Names

caspase-12

CASP-12

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01945 CASP12 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01946 Casp12 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01947 Casp12 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Casp12 NCBI NCBI:100506742