2. Gene
  3. Cdh17 - cadherin 17 Gene

Cdh17 - cadherin 17 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as HPT-1; HPT-1/LI

Gene ID: 12557 | Gene type: protein coding

About Cdh17

Summary

Enables proton-dependent oligopeptide secondary active transmembrane transporter activity. Involved in germinal center B cell differentiation; marginal zone B cell differentiation; and spleen development. Acts upstream of or within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and oligopeptide transport. Located in cell surface and plasma membrane. Is expressed in several structures, including common bile duct; gut; spleen; trunk; and urogenital sinus. Orthologous to human CDH17 (cadherin 17). [provided by Alliance of Genome Resources, Apr 2022]

Cdh17 Products(1)

mRNA Protein Name
NM_019753.4 NP_062727.1 cadherin-17 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10906147 MGI
enables proton-dependent oligopeptide secondary active transmembrane transporter activity IDA
IDA: Inferred from direct assay
8153632 MGI
Biological Process GO Annotation Evidence Reference Source
involved in B cell differentiation IMP
IMP: Inferred from mutant phenotype
15688343 MGI
NOT involved in T cell mediated immunity IMP
IMP: Inferred from mutant phenotype
15688343 MGI
acts upstream of or within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IDA
IDA: Inferred from direct assay
10906147 MGI
involved in germinal center B cell differentiation IMP
IMP: Inferred from mutant phenotype
15688343 MGI
acts upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules IDA
IDA: Inferred from direct assay
10906147 MGI
involved in marginal zone B cell differentiation IMP
IMP: Inferred from mutant phenotype
15688343 MGI
acts upstream of or within oligopeptide transport IDA
IDA: Inferred from direct assay
8153632 MGI
involved in spleen development IMP
IMP: Inferred from mutant phenotype
15688343 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
15688343 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15023525 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cadherin-17

BILL-cadherin

LI-cadherin

P130

liver-intestine cadherin

Recombinant Cdh17 Proteins

Cat. No. Product Name Accession Purity
HY-P77895 Cadherin-17 Protein, Mouse (HEK293, His) Q9R100 (F26-M786) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02327 CDH17 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990363 Anti-CDH17/Cadherin-17 Antibody (PTA001_A4) Inhibitor 98.31% Unkown
HY-P991100 Anti-CDH17/Cadherin-17 Antibody (10C12) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdh17 NCBI NCBI:1015
Macaca fascicularis Cdh17 NCBI NCBI:102129651
Rattus norvegicus Cdh17 NCBI NCBI:117048
Macaca mulatta Cdh17 NCBI NCBI:698886