2. Gene
  3. Socs3 - suppressor of cytokine signaling 3 Gene

Socs3 - suppressor of cytokine signaling 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cis3; Ef10; Ssi3; Cish3; EF-10; SSI-3

Gene ID: 12702 | Gene type: protein coding

About Socs3

Summary

Enables phosphotyrosine residue binding activity. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; negative regulation of Insulin Receptor signaling pathway; and placenta development. Predicted to be located in cytoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Is expressed in several structures, including extraembryonic component; liver; placenta; retina; and spleen. Human ortholog(s) of this gene implicated in atopic dermatitis 4. Orthologous to human SOCS3 (suppressor of cytokine signaling 3). [provided by Alliance of Genome Resources, Apr 2022]

Socs3 Products(1)

mRNA Protein Name
NM_007707.3 NP_031733.1 suppressor of cytokine signaling 3
Protein Preferred Names Protein Names

suppressor of cytokine signaling 3

CIS-3

E2a-Pbx1 target gene in fibroblasts 10

STAT-induced STAT inhibitor 3

cytokine inducible SH2-containing protein 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-155335 FPR2 agonist 3 Agonist / Unkown
HY-RS13554 SOCS3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16260 Socs3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Socs3 NCBI NCBI:9021