2. Gene
  3. Cpt1a - carnitine palmitoyltransferase 1a, liver Gene

Cpt1a - carnitine palmitoyltransferase 1a, liver Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CPTI; Cpt1; C730027G07

Gene ID: 12894 | Gene type: protein coding

About Cpt1a

Summary

Enables carnitine O-palmitoyltransferase activity and palmitoleoyltransferase activity. Predicted to be involved in several processes, including carnitine metabolic process; positive regulation of fatty acid beta-oxidation; and regulation of Insulin secretion. Predicted to act upstream of or within lipid metabolic process. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; central nervous system; integumental system; sensory organ; and urinary system. Used to study carnitine palmitoyltransferase I deficiency. Human ortholog(s) of this gene implicated in carnitine palmitoyltransferase I deficiency and lipid metabolism disorder. Orthologous to human CPT1A (carnitine palmitoyltransferase 1A). [provided by Alliance of Genome Resources, Apr 2022]

Cpt1a Products(1)

mRNA Protein Name
NM_013495.2 NP_038523.2 carnitine O-palmitoyltransferase 1, liver isoform
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables carnitine O-palmitoyltransferase activity IDA
IDA: Inferred from direct assay
12920182 MGI
enables carnitine O-palmitoyltransferase activity IMP
IMP: Inferred from mutant phenotype
16169268 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16271724 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carnitine O-palmitoyltransferase 1, liver isoform

CPT I

CPT1-L

CPTI-L

L-CPT I

carnitine palmitoyltransferase 1, liver

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-115938 BEC2 Inhibitor ≥98.0% Phase 3
Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-50202 Etomoxir Inducer 99.92% Yes
HY-12364 C75 Inhibitor 99.91% Unkown
HY-50202A Etomoxir sodium salt Inducer 99.73% Yes
HY-W588256 12-Tridecenoic acid Activator / Unkown
HY-W420033 (S)-(+)-Etomoxir Control 98.65% Unkown
HY-RS03122 CPT1A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16248 Cpt1a Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-116257 GSK-7227 Agonist / Unkown
HY-12364B (−)-C75 Inhibitor / Unkown
HY-161027 DHP-B Inducer / Unkown
HY-N8144 Niga-ichigoside F1 ≥99.0% Unkown
HY-N9333 Wistin Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cpt1a NCBI NCBI:1374