2. Gene
  3. TMEM18 - transmembrane protein 18 Gene

TMEM18 - transmembrane protein 18 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as lncND

Gene ID: 129787 | Gene type: protein coding

About TMEM18

Cytogenetic location: 2p25.3 Genomic coordinates (GRCh38): 2:663,877-677,406 (from NCBI)

This gene has 8 transcripts (splice variants) and 189 orthologues. Ubiquitous expression in ovary (RPKM 18.2), thyroid (RPKM 13.8) and 25 other tissues.

Summary

Predicted to enable DNA binding activity. Involved in cell migration. Located in nuclear membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM18 Products(3)

mRNA Protein Name
NM_001352680.2 NP_001339609.1 transmembrane protein 18 isoform 2
NM_001352681.1 NP_001339610.1 transmembrane protein 18 isoform 3
NM_152834.4 NP_690047.2 transmembrane protein 18 isoform 1

TMEM18 Protein Structure

TMEM18

TMEM18: Transmembrane protein 18 (13 - 133)

  • 0
  • 100
  • 140 a.a.
Protein Preferred Names Protein Names

transmembrane protein 18

Related Diseases

Diseases Alias
Meier-Gorlin Syndrome 4

MGORS4

Meier-Gorlin Syndrome, Type 4
Leptin Deficiency Or Dysfunction

Morbid Obesity

Obesity Due To Congenital Leptin Deficiency

LEPD

Congenital Leptin Deficiency

Obesity, Morbid

Obesity, Morbid, Due To Leptin Deficiency

Severe Obesity

Obesity, Morbid, Nonsyndromic 1

Leptin Deficiency

Obesity, Severe, Due To Leptin Deficiency

Leptin

Morbid Obesity Due To Leptin Deficiency

Obesity Morbid

Leptin Dysfunction
Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

Obesity , Susceptibility To

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14688 TMEM18 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TMEM18 MGD MGI:2387176
Felis catus TMEM18 VGNC VGNC:66295
Rattus norvegicus TMEM18 RGD RGD:1359389
Bos taurus TMEM18 VGNC VGNC:36006
Macaca mulatta TMEM18 VGNC VGNC:106238