2. Gene
  3. Epor - erythropoietin receptor Gene

Epor - erythropoietin receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 13857 | Gene type: protein coding

About Epor

Summary

Predicted to enable erythropoietin receptor activity and identical protein binding activity. Acts upstream of or within animal organ development and signal transduction. Predicted to be located in cytoplasm; external side of plasma membrane; and nuclear speck. Is expressed in several structures, including brain; egg cylinder; genitourinary system; germ layer; and heart and pericardium. Human ortholog(s) of this gene implicated in anemia; familial erythrocytosis 1; high grade glioma; polycythemia; and systemic lupus erythematosus. Orthologous to human EPOR (erythropoietin receptor). [provided by Alliance of Genome Resources, Apr 2022]

Epor Products(3)

mRNA Protein Name
NM_001411820.1 NP_001398749.1 erythropoietin receptor isoform 2
NM_001411821.1 NP_001398750.1 erythropoietin receptor isoform 3
NM_010149.4 NP_034279.3 erythropoietin receptor isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables erythropoietin receptor activity IDA
IDA: Inferred from direct assay
8341708 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15953601 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
11807041 MGI
acts upstream of or within decidualization IDA
IDA: Inferred from direct assay
17300687 MGI
acts upstream of or within embryo development IDA
IDA: Inferred from direct assay
17300687 MGI
involved in erythropoietin-mediated signaling pathway IDA
IDA: Inferred from direct assay
8341708 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
11807041 MGI
acts upstream of or within signal transduction IDA
IDA: Inferred from direct assay
17300687 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in plasma membrane IDA
IDA: Inferred from direct assay
8341708 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

erythropoietin receptor

EPO-R

Recombinant Epor Proteins

Cat. No. Product Name Accession Purity
HY-P73033 Erythropoietin receptor/EpoR Protein, Mouse (sf9, Fc) P14753 (A25-P249) ≥95%
HY-P73034 Erythropoietin receptor/EpoR Protein, Mouse (HEK293, His) P14753 (A25-P249) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18960 CHZ868 Inhibitor 99.56% Unkown
HY-W062700 STS-E412 Activator 99.72% Unkown
HY-RS04448 EPOR Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Epor NCBI NCBI:2057
Macaca fascicularis Epor NCBI NCBI:102138718
Macaca mulatta Epor NCBI NCBI:714546