2. Gene
  3. RUNDC1 - RUN domain containing 1 Gene

RUNDC1 - RUN domain containing 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RUND1

Gene ID: 146923 | Gene type: protein coding

About RUNDC1

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:42,980,565-42,995,142 (from NCBI)

This gene has 3 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in brain (RPKM 7.5), thyroid (RPKM 6.9) and 25 other tissues.

Summary

This gene encodes a protein that contains a RUN (RPIP8, UNC-14 and NESCA) domain and a coiled coil domain. The encoded protein may negatively regulate p53 transcriptional activity. This gene is a potential candidate gene for predisposition to glioma in humans. [provided by RefSeq, May 2017]

RUNDC1 Products(3)

mRNA Protein Name
NM_001321381.3 NP_001308310.2 RUN domain-containing protein 1 isoform 2
NM_001394222.1 NP_001381151.1 RUN domain-containing protein 1 isoform 3
NM_173079.5 NP_775102.3 RUN domain-containing protein 1 isoform 1

RUNDC1 Protein Structure

RUN

RUN: RUN domain (430 - 601)

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  • 613 a.a.
Protein Preferred Names Protein Names

RUN domain-containing protein 1

Related Diseases

Diseases Alias
Mitochondrial Complex Iv Deficiency, Nuclear Type 1

Cytochrome C Oxidase Deficiency

Mitochondrial Complex Iv Deficiency

Cox Deficiency

Cytochrome-C Oxidase Deficiency Disease

MC1DN4

Cytochrome-C Oxidase Deficiency

MC4DN1

Mitochondrial Complex I Deficiency, Nuclear Type 4

Complex 4 Mitochondrial Respiratory Chain Deficiency

Complex Iv Deficiency

Mitochondrial Complex 1 Deficiency, Nuclear Type 4

Nuclear Type Mitochondrial Complex I Deficiency 4

Deficiency Of Mitochondrial Respiratory Chain Complex4

MT-C4D

Complex Iv Mitochondrial Respiratory Chain Deficiency

Lethal Neonatal Cardiomyopathy Hypertrophic Due To Cytochrome C Oxidase Deficiency

Mitochondrial Complex Iv Deficiency, Nuclear, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12347 RUNDC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RUNDC1 MGD MGI:2144506
Felis catus RUNDC1 VGNC VGNC:99441
Macaca mulatta RUNDC1 VGNC VGNC:77101
Bos taurus RUNDC1 VGNC VGNC:34217
Rattus norvegicus RUNDC1 RGD RGD:1307490
Canis familiaris RUNDC1 VGNC VGNC:45806