Ptgdr2 - prostaglandin D2 receptor 2 Gene

Mus musculus

Also known as Crth2; Gpr44; Grp45

Gene ID: 14764 | Gene type: protein coding

About Ptgdr2

Chromosome 19: 10,914,524-10,919,875 forward strand.GRCm39:CM001012.3

This gene has 1 transcript (splice variant), 206 orthologues, 15 paralogues and is associated with 11 phenotypes. Broad expression in ovary adult (RPKM 2.6), subcutaneous fat pad adult (RPKM 1.9) and 15 other tissues.

Summary

Enables prostaglandin D receptor activity; prostaglandin F receptor activity; and prostaglandin J receptor activity. Acts upstream of or within several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; negative regulation of male germ cell proliferation; and positive regulation of G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human PTGDR2 (prostaglandin D2 receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ptgdr2 Products(1)

mRNA	Protein	Name
NM_009962.3	NP_034092.1	prostaglandin D2 receptor 2

Ptgdr2 Protein Structure

7tm_GPCRs

0
100
200
300
382 a.a.

Protein Preferred Names

Protein Names

prostaglandin D2 receptor 2

G-protein coupled receptor 44	PGD2 receptor
chemoattractant receptor-homologous molecule expressed on TH2 cells	prostaglandin D2 receptor CRTH2

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11371	PTGDR2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS11372	Ptgdr2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS11373	Ptgdr2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ptgdr2	NCBI	NCBI:11251

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