2. Gene
  3. Itga2 - integrin alpha 2 Gene

Itga2 - integrin alpha 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as DX5; GPIa; CD49B

Gene ID: 16398 | Gene type: protein coding

About Itga2

Summary

Enables amyloid-beta binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; positive regulation of cell migration; and positive regulation of cellular component organization. Predicted to act upstream of or within cell adhesion. Located in basal part of cell and external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; eye; and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; artery disease (multiple); blood platelet disease (multiple); diabetes mellitus (multiple); and von Willebrand's disease (multiple). Orthologous to human ITGA2 (Integrin subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Itga2 Products(1)

mRNA Protein Name
NM_008396.3 NP_032422.2 integrin alpha-2 precursor
Protein Preferred Names Protein Names

integrin alpha-2

CD49 antigen-like family member B

VLA-2 receptor, alpha 2 subunit

collagen receptor

platelet membrane glycoprotein Ia

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06948 ITGA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06949 ITGA2B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itga2 NCBI NCBI:3673
Macaca fascicularis Itga2 NCBI NCBI:102133302