2. Gene
  3. Itgb6 - integrin beta 6 Gene

Itgb6 - integrin beta 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2210409C20Rik; 4831415H04Rik

Gene ID: 16420 | Gene type: protein coding

About Itgb6

Summary

Enables Integrin binding activity. Involved in cell adhesion mediated by Integrin and transforming growth factor beta production. Acts upstream of or within with a negative effect on gene expression. Acts upstream of or within several processes, including animal organ development; hard palate development; and transmembrane receptor protein serine/threonine kinase signaling pathway. Located in external side of plasma membrane. Part of Integrin alphav-beta6 complex. Is expressed in several structures, including diaphragm; gut; limb; metanephros; and vertebral axis musculature. Used to study asthma and pulmonary emphysema. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1H. Orthologous to human ITGB6 (Integrin subunit beta 6). [provided by Alliance of Genome Resources, Apr 2022]

Itgb6 Products(2)

mRNA Protein Name
NM_001159564.1 NP_001153036.1 integrin beta-6 precursor
NM_021359.3 NP_067334.1 integrin beta-6 precursor
Protein Preferred Names Protein Names

integrin beta-6

Recombinant Itgb6 Proteins

Cat. No. Product Name Accession Purity
HY-P77723 Integrin alpha V beta 6 Protein, Mouse (HEK293, His) P43406 (F31-V988)&Q9Z0T9 (G22-N706) ≥95%
HY-P700769 ITGB6 Protein, Mouse (HEK293, His) Q9Z0T9 (G22-N706) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06970 ITGB6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itgb6 NCBI NCBI:3694
Macaca mulatta Itgb6 NCBI NCBI:700454